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Tuesday, November 14, 2017
Sunday, November 12, 2017
Friday, November 10, 2017
First Patient Enrolled in Mallinckrodt Phase 4 Trial of H.P. Acthar® Gel (Repository Corticotropin Injection) for Multiple Sclerosis Relapse
Pediatric and adult multiple sclerosis (MS) share many genetic variants suggesting similar biological processes are present, a recent study found. Major histocompatibility complex (MHC) variants beyond HLA–DRB1*15:01 and HLA–A*02 are also associated with pediatric-onset MS (POMS). Researchers comprehensively investigated the association between established MHC and non-MHC adult MS-associated variants and susceptibility to POMS. Cases with onset <18 years (n=569) and controls (n=16,251) were included. Adjusted logistic regression and meta-analyses were performed for individual risk variants and a weighted genetic risk score (wGRS) for non-MHC variants. Results were compared to adult MS cases (n= 7,588). They found:
Given the associations between smoking and comorbidities in individuals with multiple sclerosis (MS), health care providers should both (1) assess smoking history and quit attempts, and (2) encourage individuals with MS who smoke to become non-smokers and refer for treatment, as indicated, according to a recent study. In order to increase the chances that individuals will be successful in becoming non-smokers, clinicians would do well to also assess and treat depression in their patients who smoke and are also depressed. Researchers used a web-based survey to obtain cross-sectional data from 335 individuals with MS. They then examined the associations between smoking variables (current use, frequency, and quit attempts) and comorbidities, and found:
Wednesday, November 8, 2017
According to the National Multiple Sclerosis Society, around 65 percent of people living with the disease suffer from some cognitive issues — most notably, memory, concentration and speed of processing information.
If you find that you are frequently experiencing cognitive issues and that it’s affecting your daily life, you need to speak to your health care team. They’ll assess your problems and provide you with strategies to help you better deal with the situation.